Are SSRIs associated with upper gastrointestinal bleeding in adults?
Metadata[+] Show full item record
Selective serotonin reuptake inhibitor (SSRI) use is associated with a 2-fold increase in the incidence of upper gastrointestinal bleeding. Concomitant use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) with SSRIs increases the risk of upper gastrointestinal bleeding even further. (SOR B, based on a meta-analysis and systematic reviews of case-control studies.)
Evidence Based Practice 13(3): 06-07.