What are the diagnostic criteria for HELLP syndrome?
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HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome is defined as a triad of laboratory abnormalities in pregnant women. Evidence of hemolysis, evidence of hepatocyte injury, and a low platelet count all must be present, although experts do not always agree on which laboratory tests or cutoff values to use to document these pathological processes. The clinical presentation is highly variable. Pregnant women with flulike symptoms in later pregnancy and those with preeclampsia should be evaluated for the syndrome. (SOR C, based on expert opinion and extrapolation from cohort studies.)
Evidence Based Practice 13(3): 08-09.