Therapy for new-onset atrial fibrillation with rapid ventricular rate
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Intravenous (IV) non-dihydropyridine calcium-channel blockers (verapamil and diltiazem) and most IV beta-blockers rapidly reduce the ventricular response in new-onset atrial fibrillation. Although the absolute decrease in heart rate is greater with diltiazem than with metoprolol in the first 20 minutes, the clinical importance of this difference is unclear.
Evidence Based Practice 13(4): 01-02.