How accurate is MRI for detecting breast cancer in high-risk women?
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In high-risk women between the ages of 40 and 47, breast magnetic resonance imaging (MRI) detects all forms of breast cancer, with a sensitivity of 51% to 100% and a specificity of 75% to 98%, yielding a wide positive predictive value (PPV) range of 7% to 79%. Compared with mammography, MRI demonstrates an overall higher sensitivity for detection of invasive breast cancers, whereas mammography consistently has a higher sensitivity for ductal carcinoma in situ (DCIS). The American Cancer Society (ACS) recommends annual MRI along with mammography in protocols for screening high-risk women.
Evidence Based Practice 13(6): 1-2.