What is the best way to manage asymptomatic Chlamydia infections found on screening nonpregnant women?
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Nonpregnant women with Chlamydia should be treated with azithromycin or doxycycline. (SOR A, based on a meta-analysis.) Alternative therapies include erythromycin, levofloxacin, or ofloxacin, with preference for antibiotics being dispensed on site and directly observed. (SOR C, based on consensus guideline.) Further management should include patient-delivered partner therapy (SOR A, based on a meta-analysis) and abstinence until 7 days posttreatment for both patient and partners, and retesting at 3 to 12 months after therapy (SOR C, based on consensus guideline).
Evidence Based Practice 13(6): 11.