What is the best initial management of grade I and grade II ankle sprain?
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In addition to rest, ice, compression, elevation, and nonsteroidal anti-inflammatory drugs (NSAIDs), functional treatment of ankle sprains improves certain outcomes compared with immobilization. Evidence is insufficient to determine which functional treatment is superior, and the effectiveness of surgery compared with conservative modalities remains unclear. (SOR B, based on systematic reviews of limited-quality studies.)
Evidence Based Practice 13(7): 06.