Clinical Inquiries, 2020
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Recent Submissions
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Introduction to Clinical Inquiries : new series by the Family Physicians Inquiries Network
(Family Physicians Inquiries Network, 2020)Introduction to Clinical Inquiries and FPIN. The Clinical Inquiries were included in Canadian Family Physician beginning March 2020. -
Acupuncture for low back pain
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Is acupuncture effective in improving pain relief for low back pain? Evidence-based answer: Acupuncture is an effective treatment for relief from low back pain, even when compared with other ... -
Efficacy of a low-carbohydrate or ketogenic diet in preventing patient morbidity and mortality
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What is the efficacy of a low-carbohydrate or ketogenic diet in the prevention of patient morbidity and mortality? Evidence-based answer: Ketogenic diets can reduce seizure incidence in refractory ... -
Hypoglycemia with insulin and sulfonylureas
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: In patients with type 2 diabetes mellitus (T2DM), does the combination of insulin and sulfonylurea (SU) increase the risk of hypoglycemia? Evidence-based answer: The incidence of severe ... -
Chlamydia test-of-cure in pregnancy
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What is the optimal interval between treatment and test-of-cure (TOC) in pregnant women with Chlamydia trachomatis (CT)? Evidence-based answer: The optimal interval between treatment and TOC ... -
Effect of corticosteroids on pain and function in knee osteoarthritis patients
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Does the type of corticosteroid have an effect on pain and functional status of the knee in osteoarthritis (OA) patients receiving intra-articular injections? Evidence-based answer: In patients ... -
Effective analgesic options for intrauterine device placement pain
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What analgesic options are most effective for pain related to intrauterine device (IUD) placement? Evidence-based answer: Lidocaine-prilocaine cream (LPC; 2.5% lidocaine and 2.5% prilocaine) ... -
Potential harms of long-term acne treatment with oral antibiotics
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What are the potential harms of long-term acne treatment with oral antibiotics? Evidence-based answer: Specific evidence attributing adverse effects to long-term acne treatment with oral ... -
Effectiveness of dermoscopy in skin cancer diagnosis
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Does dermoscopy improve the effectiveness of skin cancer diagnosis when used for skin cancer screening? Evidence-based answer: Dermoscopy added to visual inspection is more accurate than visual ... -
Platelet-rich plasma injection for rotator cuff disease
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Is platelet-rich plasma (PRP) injection an effective treatment for rotator cuff disease? Evidence-based answer: In non-operative treatment of rotator cuff injuries, PRP injection did not improve ... -
Association of first-line antidepressants and incident adverse metabolic effects
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Are first-line antidepressants associated with incident adverse metabolic effects in adults? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs) and bupropion statistically ... -
Does vitamin D supplementation reduce asthma exacerbations?
(Family Physicians Inquiries Network, 2020)Q: Does vitamin D supplementation reduce asthma exacerbations? Evidence-based answer: YES, to some extent it does, and primarily in patients with low vitamin D levels. Supplementation reduces asthma exacerbations requiring ... -
Do prophylactic antipyretics reduce vaccination-associated symptoms in children?
(Family Physicians Inquiries Network, 2020)Q: Do prophylactic antipyretics reduce vaccination-associated symptoms in children? Yes for acetaminophen, not so much for ibuprofen. Prophylactic acetaminophen reduces the odds of febrile reactions in the first 48 hours ... -
Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone?
(Family Physicians Inquiries Network, 2020)Q: Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone? Evidence-based answer: Yes. Monthly extended-release injectable naltrexone (XR-NTX) treats opioid use disorder as ... -
Do electronic reminder systems help patients with T2DM to lose weight?
(Family Physicians Inquiries Network, 2020)Q: Do electronic reminder systems help patients with T2DM to lose weight? Evidence-based answer: PROBABLY NOT--but they may augment self-management. Four-component telehealth systems--including electronic reminders, measuring ... -
Does early introduction of peanuts to an infant's diet reduce the risk for peanut allergy?
(Family Physicians Inquiries Network, 2020)Q: Does early introduction of peanuts to an infant's diet reduce the risk for peanut allergy? Evidence-based answer: Probably not, unless the child has severe eczema or egg allergy. In a general pediatric population, ... -
Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See ... -
Which medications work best for menorrhagia?
(Family Physicians Inquiries Network, 2020)Q: Which medications work best for menorrhagia? Evidence-based answer: Four medications have been shown to reduce menstrual blood loss (MBL) significantly in placebo-controlled randomized controlled trials (RCTs): the ... -
Does concurrent use of clopidogrel and PPIs increase CV risk in patients with ACS?
(Family Physicians Inquiries Network, 2020)Q: Does concurrent use of clopidogrel and PPIs increase CV risk in patients with ACS? Evidence-based answer: No. Adding a proton pump inhibitor (PPI) in patients taking antiplatelet medications such as clopidogrel for acute ... -
Do cinnamon supplements improve glycemic control in adults with T2DM?
(Family Physicians Inquiries Network, 2020)Q: Do cinnamon supplements improve glycemic control in adults with T2DM? Evidence-based answer: the answer isn't clear. Cinnamon supplements for adults with type 2 diabetes haven't been shown to decrease hemoglobin A1C ...