Browsing Department of Chemistry (UMKC) by Thesis Semester "2013 Spring"
Now showing items 1-10 of 10
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Biogeochemistry and inorganic geochemistry as indicators of the paleoenvironment and paleohydrology of the Al-Azraq Basin, Jordan
(2013)This study investigates the biogeochemical and inorganic geochemical indicators for past environments and paleohydrology of a high resolution sediment record from the Al-Azraq Basin, Jordan. The second largest basin in ... -
Design and optimization of nanoformulation loaded with HIV microbicides
(2013)The objective of this dissertation is to design and optimize nanoformulation for microbicides intended for the prevention of HIV/AIDS transmission. In chapters 1 and 2, the aims and the scope of this work are introduced, ... -
Design, synthesis and evaluation of novel intercalator analogs targeting therapeutically important polymerases and folded RNA
(2013)Polymerases and ribonucleic acids have been found to play major roles in the causation and progression of several diseases. Targeting such important therapeutic targets using small molecules can help achieve their specific ... -
Development and characterization of advanced nitric oxide-delivering polymeric systems against cardiovascular complications
(2013)Valvular complications and atherosclerosis contribute to the majority of the cardiovascular disease related deaths worldwide. In this thesis project the role of normative tissue mineral concentrations in native and ... -
Effects of pressure and temperature on the yield strength of tantalum and rhenium
(2013)The effects of pressure and temperature on the yield strength of tantalum and the effects of pressure on the yield strength of rhenium were investigated using ruby fluorescence. A new Raman system with a motorized stage ... -
Enantioselective hydrolysis of 1-arylpropargylic esters by enzymatic kinetic resolution and dynamic kinetic resolution of 1-arylallylic esters
(2013)Chiral 1-arylprop-2-en-1-ols and 1-arylprop-2-yn-1-ols are useful building blocks for modern pharmaceuticals. Previous work has found that enzyme catalysis is a potential new enantioselective synthetic route to the former. ... -
Light-activated biomacromolecules
(2013)Biomacromolecules, mainly nucleic acids and proteins, are involved in every cellular process and therefore their aberrant level or function is linked with most of the diseases. Controlling these macromolecules using light ... -
Novel drug interaction for improving intracellular accumulation and efficacy of chemotherapeutics in retinoblastoma and mitochondrial localization of transporters in corneal epithelial cells
(University of Missouri--Kansas City, 2013-03-15)Chemoreduction is the key treatment for retinoblastoma management. However, anticancer agents suffer from poor cell permeability and chemoresistance due to major interaction with multidrug resistant (MDR) efflux proteins ... -
Pressure-induced phase transitions in select molybdates and tungstates
(2013)Mao-Bell and symmetric diamond anvil cells were used to study the effect of high-pressure on a series of tungstate and molybdate compounds. The experimental techniques of powder x-ray diffraction and Raman spectroscopy ... -
Structural and enzymatic characterization of bacterial cell wall enzymes: focus on penicillin-binding proteins
(2013)The research presented in this dissertation was aimed at understanding several structural and biochemical features underlying the bacterial cell wall biosynthetic process using statistical, biochemical and analytical tools. ...