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Ontology-based methods for disease similarity estimation and drug repositioning
(University of Missouri--Kansas City, 2012-10-02)
Human genome sequencing and new biological data generation techniques have provided an opportunity to uncover mechanisms in human disease. Using gene-disease data, recent research has increasingly shown that many seemingly ...
Sequential Designs with Application in Software Engineering
(2014-03-31)
Presented here is a Bayesian approach to test case allocation in the software reliability estimation. Bayesian analysis allows us to update our beliefs about the reliability of a particular partition as we test, and thus, ...
Measuring Level of Degradation in Power Semiconductor Devices using Emerging Techniques
(2021)
High thermal and electrical stress, over a period of time tends to deteriorate the health of power electronic switches. Being a key element in any high-power converter systems, power switches such as insulated-gate bipolar ...
RUPEE: A Big Data Approach to Indexing and Searching Protein Structures
(2021)
Given the close relationship between protein structure and function, protein structure searches have long played an established role in bioinformatics. Despite their maturity, existing protein structure searches either ...