Browsing Division of Cell Biology and Biophysics (UMKC) by Thesis Semester "2017 Fall"
Now showing items 1-4 of 4
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Biochemical and Structural Studies of the Role of FKBP(L)s in the fly and Mammalian Circadian Cycle
(University of Missouri -- Kansas City, 2017)FK506 binding-like proteins (FKBPLs) are proteins that structurally resemble the immunophilins. Their functions in cell signaling include protein folding, molecular trafficking, RNA splicing and cell cycle regulation ... -
A Genetic Screen for Tribbles Suppressors Identifies the E3 Ubiquitin Ligase Neuralized as a Novel Target
(University of Missouri -- Kansas City, 2017)In this dissertation, I used the Drosophila wing as a model tissue for a genetic screen to identify novel targets of Tribbles. Drosophila Tribbles is the founding member of a family of pseudokinases conserved between ... -
Regulation of Antimicrobial Peptide Genes in Insects by the Toll Pathway and NF-kB Transcription Factors
(University of Missouri--Kansas City, 2017)Insects lack adaptive immunity and solely rely on innate immunity to combat pathogens. Innate immunity in dipteran and lepidopteran insects mainly depends on two canonical pathways, the Toll pathway that provides ... -
Structural Basis for the Regulation of the Ceramide Transfer Protein
(University of Missouri -- Kansas City, 2017)Ceramide, a central intermediate in sphingolipid metabolism, is synthesized at the endoplasmic reticulum (ER) and transferred to the Golgi by the ceramide transfer (CERT) protein for conversion to sphingomyelin (SM). ...