Browsing College of Engineering (MU) by Thesis Department "Informatics (MU)"
Now showing items 1-20 of 30
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Accelerating data-driven discover in type 1 diabetes: an informatics-based approach
(University of Missouri--Columbia, 2022)Type 1 diabetes (T1D) is a lifelong chronic disease characterized by the absolute or near-absolute loss of insulin. For affected individuals, management of T1D is an unremitting challenge that involves constant blood glucose ... -
Alternative applications of whole genome de novo assembly in animal genomics /
(University of Missouri--Columbia, 2017)Genome sequencing is the process by which the sequence of deoxyribonucleic acid (DNA) residues that compromise the genome, or complete set of genetic materials of an organism or individual, is determined. Down-stream ... -
Analyzing high-throughput genomics data for cancer studies
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] NGS data output has increased at a rate that outpaces Moore's law, more than doubling each year since it was invented. Studying such high-throughput ... -
Artificial intelligence driven framework for the structurization of free-text diagnostic reports
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Free-text sections of diagnostic reports contain a wealth of data on patients, diseases, and complex diagnostic processes. However, free-text data are ... -
Challenges and opportunities in diabetes self-management education and support : the analyses of diabetes mobile applications and provider documentation patterns
(University of Missouri--Columbia, 2020)Diabetes mellitus is one of the most prevalent chronic diseases in the United States. As a disease with long-term complications requiring changes in management, diabetes requires not only education at the time of diagnosis, ... -
Comparative machine learning approach for biomarker identification using multiomics data from patients with endometriosis
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Endometriosis is a complex and common gynecological disorder yet a poorly understood disease affecting about 176 million women worldwide, and causing ... -
Design and development of geospatial analytical research knowledgebase (GeoARK)
(University of Missouri--Columbia, 2022)Enabling the use of spatial context is vital to understanding today's digital health problems. Any given location is associated with many different contexts. It is paramount to build a robust spatial data analytics framework ... -
Determining the impact of usability issues of primary care physicians by expertise when using an electronic health record
(University of Missouri--Columbia, 2015)Background: EHRs with poor usability present steep learning curves for new resident physicians, who are already overwhelmed in learning a new specialty. This may lead to error prone use of EHR in medical practice by new ... -
Development of a multi-omics approach to identify highly correlated transcriptomic, proteomic and metabolic signatures in maize B73 and FR697 drought stressed nodal roots
(University of Missouri--Columbia, 2021)Maize is one of the most important crops grown in the continental US and worldwide, and as such, major interest is directed towards understanding the impact of drought conditions on maize growth and development. Nodal ... -
Development of Soybean Knowledge Base (SoyKB), a multi-omics data integration web resource for bridging molecular breeding and translational genomics in Glycine Max
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Many genome-scale data are available in soybean (Glycine Max) including genomics, transcriptomics, proteomics and metabolomics datasets, together with ... -
Electronic health record system implementation processes at critical access hospitals
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The US government allocated $30 billion to implement electronic health records (EHRs) in hospitals and provider practices through policy addressing ... -
Evaluating usability, effectiveness, and usage of telehealth technologies /
(University of Missouri--Columbia, 2014)Affordable Care Act (ACA) has allowed more patients that did not previously have health care insurance to have coverage and access to care. This increase in the number of patients seeking medical care will only add additional ... -
An evaluation of an Electronic Medical Record (EMR) based system to characterize and correlate physician burnout and EMR use
(University of Missouri--Columbia, 2021)Burnout disproportionately affects healthcare workers and continues to rise, contributing to cost, quality, and patient safety risk in an already overburdened United States healthcare system. While the causes of burnout ... -
Explainable artificial intelligence for patient stratification and drug repositioning
(University of Missouri--Columbia, 2021)Enabling precision medicine requires developing robust patient stratification methods as well as drugs tailored to homogeneous subgroups of patients from a heterogeneous population. Developing de novo drugs is expensive ... -
Explainable artificial intelligence to stratify pan-cancer patients for immune checkpoint inhibitor decision making
(University of Missouri--Columbia, 2022)Immune checkpoints are a normal part of the immune system. It engages when proteins on the surface of immune cells called T cells recognize and bind to partner proteins on other cells, such as some tumor cells. Immune based ... -
Homology sequence analysis using GPU acceleration
(University of Missouri--Columbia, 2018)A number of problems in bioinformatics, systems biology and computational biology field require abstracting physical entities to mathematical or computational models. In such studies, the computational paradigms often ... -
Informatic approaches to evolutionary systems biology
(University of Missouri--Columbia, 2013)The sheer complexity of evolutionary systems biology requires us to develop more sophisticated tools for analysis, as well as more probing and biologically relevant representations of the data. My research has focused on ... -
Informatics strategies for risk stratification in population health management
(University of Missouri--Columbia, 2017)Risk analysis and population health management can improve health outcomes, but improved risk stratification is needed to manage healthcare costs. Analysis of 157 publications on translational implementations of "risk ... -
Integrated clinical decision support : assessing opportunities and outcomes
(University of Missouri--Columbia, 2019)Medical calculators play an important role as a component of specific clinical decision support (CDS) systems that synthesize measurable evidence and can introduce new medical guidelines and standards. Understanding the ... -
An interventional informatics approach to development and evaluation of population-based health and web technologies
(University of Missouri--Columbia, 2017)Interventional informatics is the use of health information technology (HIT) that drives evidence-based and evidence-generating practices to inform an improved health delivery system. Current HIT lacks movement towards ...