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Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor
(Interdisciplinary Doctoral Student Council at the University of Missouri- Kansas City, 2007)
Polarized epithelial non-human (canine) cell lines stably transfected with human or murine complementary DNA (cDNA) encoding for various efflux transporters (P-gp/MDR1, MRP1, MRP2, and Bcrp1) were used to study transepithelial ...
Correlation between thyroid hormone status and hepatic hyperplasia and hypertrophy caused by the peroxisome proliferator-activated receptor alpha agonist Wy-14,643
(2004-05-24)
Abstract
Background
The metabolic inhibitor rotenone inhibits hepatocellular proliferation and the incidence of liver cancer ...
Glucocorticoid-like effects of antihepatocarcinogen Rotenone are mediated viaenhanced serum corticosterone levels: Molecular Fitting and Receptor Activation Studies
(2003-02-14)
Abstract
Background
Recent studies suggest that rotenone alters cell signal transduction pathways in a manner similar to glucocorticoids. ...
Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitrostudy
(2004-01-12)
Abstract
Background
Intravenous iron is typically administered during the hemodialysis (HD) procedure. HD patients may be prescribed ...
Hepatocarcinogenic potential of the glucocorticoid antagonist RU486 in B6C3F1 mice: effect on apoptosis, expression of oncogenes and the tumor suppressor gene p53
(2003-01-03)
Abstract
Background
Glucocorticoids inhibit hepatocellular proliferation and modulate the expression of oncogenes and tumor ...
Medication-related problem type and appearance rate in ambulatory hemodialysis patients
(2003-12-22)
Abstract
Background
Hemodialysis (HD) patients are at risk for medication-related problems (MRP). The MRP number, type, and appearance ...
Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha:a role for kupffer cells?
(2006-11-27)
Abstract
Background
It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release ...