Browsing 2010 Dissertations (MU) by Title "Functional and pharmacological importance of the composite ATP binding site 1 in CFTR chloride channels"
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Functional and pharmacological importance of the composite ATP binding site 1 in CFTR chloride channels
(University of Missouri--Columbia, 2010)The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride ion channel whose defects cause the deadly genetic disease cystic fibrosis (CF). Like other ATP binding cassette (ABC) proteins, CFTR encompasses ...