Platelet-rich plasma injection for rotator cuff disease
Abstract
Clinical Inquiries question: Is platelet-rich plasma (PRP) injection an effective treatment for rotator cuff disease? Evidence-based answer: In non-operative treatment of rotator cuff injuries, PRP injection did not improve functional outcomes or pain scores when compared with saline solution placebo, dry needling, or corticosteroid injection (strength of recommendation A: systematic review of randomized controlled trials [RCTs] with some methodologic flaws). Surgical adjunctive PRP injection inconsistently produced statistically significant improvements in pain and function of minimal clinical significance (less than 5%) (strength of recommendation B: systematic review of RCTs). Overall, PRP injection in the treatment of rotator cuff disease showed inconsistent results with moderate to high risk of bias.
Citation
Canadian Family Physician | Le Médecin de famille canadien } Vol 66: NOVEMBER | NOVEMBRE 2020, pp 824-826
Rights
OpenAccess.
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