What is the best treatment for chronic anal fissures?
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Nitroglycerine (NTG) ointment, botulinum toxin, and topical calcium channel blockers are all effective for managing anal fissures. (SOR: A, based on systematic reviews and meta-analyses.) Lateral internal sphincterotomy (LIS) is the preferred surgical procedure, with a higher healing rate and lower recurrence rate than medical therapy. (SOR: A, based on systematic reviews and meta-analyses.)
Evidence-based practice 13, no. 08 (2010): 12