Take-all is a disease of the roots, crown, and stem base of wheat. It interrupts plant development and may seriously suppress yields. A common problem of winter wheat in North America, Take-all occurs in Missouri especially under cool, damp conditions. The name originated in Australia in the middle of the last century when the disease "took all" seedlings it attacked. In Missouri the disease seldom affects seedlings but more commonly attacks wheat plants at the tillering stage. This publication provides a description of the disease as well as some tips on how to control it.