What are the best treatment options for Friedreich ataxia (FA)?
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The free-radical scavenger idebenone has been shown to be more effective than placebo in decreasing interventricular septal (IVS) thickness and left ventricular mass (LVM) in FA patients. The drug may also yield improvement in neurologic function at high doses. (SOR: B, based on 2 small RCTs.)
Evidence-based practice 13, no. 09 (2010): 08-09