When should caretakers consider stopping cognition-enhancing medications in patients with dementia?
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Cognition-enhancing medications in patients with dementia should be discontinued when the patient (a) decides to stop; (b) refuses to take the medication; (c) is nonadherent; (d) shows no response to therapy; (e) experiences intolerable side effects; (f) has comorbidities that make continued use either unacceptably risky or futile; or (g) has end-stage dementia. (SOR: C, based on consensus guidelines.)
Evidence Based Practice 13(9): 10-11.