Pyogenic liver abscess and gastrointestinal lemierre syndrome due to fusobacterium nucleatum
Metadata[+] Show full item record
Pyogenic liver abscess (PLA) affects men disproportionately to women and is occurring with increasing incidence. The mortality associated with PLA nears 15% in the Western world. PLA constitutes a significant number of total liver abscesses and can rarely be caused by the gram-negative bacilli, Fusobacterium. Virulent strains of Fusobacterium have been described as a rare cause of thrombophlebitis and metastatic abscesses. Fusobacterium necrophorum is specifically implicated in the development of Lemierre syndrome (LS) which comprises periodontal abscess and internal jugular vein thrombosis. Similar infection involving intra-abdominal abscess and abdominal vessel thrombosis suggests a gastrointestinal (GI) variant of LS. We describe a case of liver abscesses and hepatic vein septic thrombosis due to Fusobacterium nucleatum in a healthy adult male patient without significant risk factors.
Am j Hosp Med 2021 Jan;5(1):2021
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.