Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire

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Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/8676

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Title: Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire
Author: Applebaum, Katie M.; Karagas, Margaret R.; Hunter, David J. (David John); Catalano, Paul J.; Byler, Steven H.; Morris, Steve; Nelson, Heather H.
Date: 2007-08
Publisher: Environmental Health Perspectives
Citation: Environmental Health Perspectives, 115(8), 2007.
Abstract: Arsenic exposure may alter the efficiency of DNA repair. UV damage is specifically repaired by nucleotide excision repair (NER), and common genetic variants in NER may increase risk for non-melanoma skin cancer (NMSC). We tested whether polymorphisms in the NER genes XPA (A23G) and XPD (Asp312Asn and Lys751Gln) modify the association between arsenic and NMSC.
URI: http://hdl.handle.net/10355/8676

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