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    Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire

    Applebaum, Katie M.
    Karagas, Margaret R.
    Hunter, David J. (David John)
    Catalano, Paul J.
    Byler, Steven H.
    Morris, Steve
    Nelson, Heather H.
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    [PDF] PolymorphismsNucleotideExcisionRepareGenes.pdf (143.2Kb)
    Date
    2007
    Format
    Article
    Metadata
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    Abstract
    Arsenic exposure may alter the efficiency of DNA repair. UV damage is specifically repaired by nucleotide excision repair (NER), and common genetic variants in NER may increase risk for non-melanoma skin cancer (NMSC). We tested whether polymorphisms in the NER genes XPA (A23G) and XPD (Asp312Asn and Lys751Gln) modify the association between arsenic and NMSC.
    URI
    http://hdl.handle.net/10355/8676
    Part of
    Missouri Research Reactor publications (MU)
    Citation
    Environmental Health Perspectives, 115(8), 2007.
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    • Missouri Research Reactor publications (MU)

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