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Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire
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Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire
Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/8676
| Title: | Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire |
| Author: | Applebaum, Katie M.; Karagas, Margaret R.; Hunter, David J. (David John); Catalano, Paul J.; Byler, Steven H.; Morris, Steve; Nelson, Heather H. |
| Date: | 2007-08 |
| Publisher: | Environmental Health Perspectives |
| Citation: | Environmental Health Perspectives, 115(8), 2007. |
| Abstract: | Arsenic exposure may alter the efficiency of DNA repair. UV damage is specifically repaired by nucleotide excision repair (NER), and common genetic variants in NER may increase risk for non-melanoma skin cancer (NMSC). We tested whether polymorphisms in the NER genes XPA (A23G) and XPD (Asp312Asn and Lys751Gln) modify the association between arsenic and NMSC. |
| URI: | http://hdl.handle.net/10355/8676 |
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Missouri Research Reactor publications (MU) [25]
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