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Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire

URI
http://hdl.handle.net/10355/8676
dc.contributor.authorApplebaum, Katie M.eng
dc.contributor.authorKaragas, Margaret R.eng
dc.contributor.authorHunter, David J. (David John)eng
dc.contributor.authorCatalano, Paul J.eng
dc.contributor.authorByler, Steven H.eng
dc.contributor.authorMorris, Steveeng
dc.contributor.authorNelson, Heather H.eng
dc.date.issued2007eng
dc.descriptiondoi:10.1289/ehp.10096eng
dc.description.abstractArsenic exposure may alter the efficiency of DNA repair. UV damage is specifically repaired by nucleotide excision repair (NER), and common genetic variants in NER may increase risk for non-melanoma skin cancer (NMSC). We tested whether polymorphisms in the NER genes XPA (A23G) and XPD (Asp312Asn and Lys751Gln) modify the association between arsenic and NMSC.eng
dc.description.sponsorshipThis work was supported by grants R01CA082354, R01CA57494, P42 ES07373, and T32 ES07155 from the National Institutes of Health.eng
dc.identifier.citationEnvironmental Health Perspectives, 115(8), 2007.eng
dc.identifier.urihttp://hdl.handle.net/10355/8676eng
dc.languageEnglisheng
dc.publisherEnvironmental Health Perspectiveseng
dc.relation.ispartofMissouri Research Reactor publications (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. University of Missouri Research Reactor Centereng
dc.sourceHarvested from: Environmental Health Perspectives Web site [http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.10096]eng
dc.subject.lcshGroundwater -- Arsenic contenteng
dc.subject.lcshSkin -- Cancereng
dc.subject.lcshCarcinogenseng
dc.subject.lcshDNA repaireng
dc.titlePolymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshireeng
dc.typeArticleeng


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