Atypical pulmonary presentation of strongyloides stercoralis hyperinfection in a patient with Philadelphia chromosome-positive acute lympoblastic leukemia : case report
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Strongyloides stercoralis is a soil-transmitted helminth endemic to tropical and subtropical regions. Rhabditiform larvae in moist soil can develop into filariform larvae that can penetrate human skin and migrate through the circulation to the lungs.1,2 These larvae escape to the alveolar space and migrate to the pharynx. Larvae can settle in the small intestine and mature into adults afterbeing swallowed in pharyngeal secretion. In immunocompromised patients, the parasite can cause autoinfection with progression to hyperinfection syndrome. We present a case of Strongyloides stercoralis hyperinfection in a patient who is immunosuppressed secondary to hyper-CVAD chemotherapy regimen for Ph+ ALL.
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