Effects of Inhomogeneous Myofibril Morphology on Optical Diffraction in Single Muscle Fibers

MOspace/Manakin Repository

Breadcrumbs Navigation

Effects of Inhomogeneous Myofibril Morphology on Optical Diffraction in Single Muscle Fibers

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/9042

[+] show full item record


Title: Effects of Inhomogeneous Myofibril Morphology on Optical Diffraction in Single Muscle Fibers
Author: Ranasinghesagara, Janaka C.; Yao, Gang, Ph. D.
Keywords: inhomogeneous sarcomere morphologies
Date: 2008-12
Publisher: The Optical Society of America
Citation: Journal of the Optical Society of America, Vol. 25, Issue 12, pp. 3051-3058 (2008).
Abstract: Laser diffraction is commonly used in physiological research that explores single muscle fibers. Although variations in sarcomere morphological properties have often been observed, their effects on laser diffraction have not been studied in detail. In this study, we applied three-dimensional coupled wave theory to a physical sarcomere model to investigate the effects of inhomogeneous morphological profiles in muscle fibers. The simulation results were compared with several of those of published experimental studies. Our results indicate that by incorporating various myofibril inhomogeneities such as skew and domain effect in the theoretical model, a variety of observations in single fiber diffraction under different experimental conditions can be reproduced in the simulation.
URI: http://hdl.handle.net/10355/9042
ISSN: 1084-7529/08/123051-8/$15.00

This item appears in the following Collection(s)

[+] show full item record