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dc.contributor.authorRanasinghesagara, Janaka C.eng
dc.contributor.authorYao, Gang, Ph. D.eng
dc.date.issued2008-12eng
dc.descriptiondoi:10.1364/JOSAA.25.003051eng
dc.description.abstractLaser diffraction is commonly used in physiological research that explores single muscle fibers. Although variations in sarcomere morphological properties have often been observed, their effects on laser diffraction have not been studied in detail. In this study, we applied three-dimensional coupled wave theory to a physical sarcomere model to investigate the effects of inhomogeneous morphological profiles in muscle fibers. The simulation results were compared with several of those of published experimental studies. Our results indicate that by incorporating various myofibril inhomogeneities such as skew and domain effect in the theoretical model, a variety of observations in single fiber diffraction under different experimental conditions can be reproduced in the simulation.eng
dc.description.sponsorshipThis project was supported in part by National Science Foundation (NSF) grant CBET-0643190 and by the National Research Initiative (NRI) of the United States Department of Agriculture (USDA) Cooperative State Research, Education and Extension Service under grant 2006-35503-17619.eng
dc.identifier.citationJournal of the Optical Society of America, Vol. 25, Issue 12, pp. 3051-3058 (2008).eng
dc.identifier.issn1084-7529/08/123051-8/$15.00eng
dc.identifier.urihttp://hdl.handle.net/10355/9042eng
dc.languageEnglisheng
dc.publisherThe Optical Society of Americaeng
dc.relation.ispartofcollectionBiological Engineering publications (MU)eng
dc.relation.ispartofcommunityUniversity of Missouri-Columbia. College of Agriculture, Food and Natural Resources. Division of Food Systems and Bioengineering. Department of Biological Engineeringeng
dc.source.harvestedOptics InfoBase Web siteeng
dc.subjectinhomogeneous sarcomere morphologieseng
dc.subject.lcshMuscle cellseng
dc.subject.lcshDiffractioneng
dc.subject.lcshWave theory of lighteng
dc.titleEffects of Inhomogeneous Myofibril Morphology on Optical Diffraction in Single Muscle Fiberseng
dc.typeArticleeng


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