Recent Submissions

  • Does platelet-rich plasma improve patellar tendinopathy symptoms? 

    Wolfenden, Emily; Vukelic, Brian; DeMarco, Matthew; Knox, Jordan; Ose, Dominik (2022-05)
    Q: Does platelet-rich plasma improve patellar tendinopathy symptoms? Evidence-based answer: IT’S UNCLEAR. High-quality data have not consistently established the effectiveness of platelet-rich plasma (PRP) injections to ...
  • Should we stop prescribing IM progesterone to women with a history of preterm labor? 

    Dresang, Lee; Vellardita, Lia (2022-01)
    Q: Should we stop prescribing IM progesterone to women with a history of preterm labor? Evidence-based answer: YES, we should stop the routine prescribing of IM progesterone to prevent preterm delivery. A 2003 randomized ...
  • Are SERMs safe and effective for the treatment of hypogonadism in men? 

    Joseph, Tina; Gibbs, Lawrence M.; Pham, Kim (2022-01)
    Q: Are SERMs safe and effective for the treatment of hypogonadism in men? Evidence-based answer: YES. For both normal-weight and obese men with low testosterone levels and hypogonadal symptoms, selective estrogen receptor ...
  • Does adjunctive oxytocin infusion during balloon cervical ripening improve labor induction? 

    Dubay, Rachel; Rentschler, Nicola; Jolly, Dara; Neher, Jon O.; Safranek, Sarah (2022-03)
    Q: Does adjunctive oxytocin infusion during balloon cervical ripening improve labor induction? Evidence-based answer: YES. Compared to the use of a transcervical balloon alone, combined cervical ripening with a balloon ...
  • Is bicarbonate therapy effective in preventing CKD progression? 

    Ahmad, Harls; Wertin, Theresa; Zhang, Yilin; Neher, Jon O.; Auten, Beth (2022-04)
    Q: Is bicarbonate therapy effective in preventing CKD progression? Evidence-based answer: YES. Long-term sodium bicarbonate therapy slightly slows the loss of renal function in patients with chronic kidney disease (CKD) ...
  • Is nonoperative treatment effective for acute Achilles tendon rupture? 

    Silver, Sabrina; Fulleborn, Stephanie; Feola, Nolan; Giblin, Sydney (2022-06)
    Q: Is nonoperative treatment effective for acute Achilles tendon rupture? Evidence-based answer: YES. Nonoperative and open surgical interventions provide equal long-term functional outcomes of the affected Achilles tendon ...
  • Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression? 

    Bleacher, Heather; Koerperich, Lindsay; Malam, Naomi; DeSanto, Kristen (2022-07)
    Q: Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression? Evidence-based answer: YES. Augmentation with second-generation antipsychotics, especially aripiprazole and quetiapine, appears ...
  • Do behavioral interventions improve nighttime sleep in children < 1 year old? 

    Hungenberg, Morgan; Houss, BreAnna; Narayan, Madhav; Lyon, Corey; DeSanto, Kristen (2022-07)
    Q: Do behavioral interventions improve nighttime sleep in children < 1 year old? Evidence-based answer: YES. Infants respond to behavioral interventions, although objective data are limited. Behavioral interventions include ...