Absence of dystrophin alters the passive properties of the extensor digitorum longus muscle in mice

MOspace/Manakin Repository

Breadcrumbs Navigation

Absence of dystrophin alters the passive properties of the extensor digitorum longus muscle in mice

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/9148

[+] show full item record


Title: Absence of dystrophin alters the passive properties of the extensor digitorum longus muscle in mice
Author: Hakim, Chady H.
Keywords: muscle degeneration
genetic disorder
Date: 2010-11-11
Abstract: Dystrophin is a cytoskeletal protein not directly participating the myosin-actin contractile apparatus in muscle. The loss of dystrophin leads to Duchenne muscular dystrophy. It is well-established that contractility is reduced in dystrophin-null muscle. Surprisingly, little is known about the influences of dystrophin-deficiency on the passive properties of muscle. We hypothesize that the loss of dystrophin alters the passive properties of the skeletal muscle. To test this hypothesis, we examined the passive properties of the extensor digitorum longus (EDL) muscle from normal BL10 and dystrophin-null mdx mice.
URI: http://hdl.handle.net/10355/9148

This item appears in the following Collection(s)

[+] show full item record