Browsing 2022 MU Dissertations - Freely available online by Thesis Department "Biochemistry (MU)"
Now showing items 1-3 of 3
-
Cryo-EM reveals how adeno-associated virus engages its receptor AAVR and an investigation of the GPR108 ectodomain
(University of Missouri--Columbia, 2022)Adeno-associated virus is one of the leading delivery agents used in gene therapy today. While it is already used in the clinic, some aspects of its basic biology are still not yet fully understood. Only recently in 2017 ... -
Informatically-informed biochemical characterization of aptamer-protein complexes
(University of Missouri--Columbia, 2022)Nucleic acid aptamers are single-stranded oligonucleotides that fold into unique three-dimensional shapes that typically bind to targets of interest with high specificity and high affinity. However, a significant limiting ... -
Single cell-type metabolomics of Medicago truncatula border cells and their roles in host-microbe interactions
(University of Missouri--Columbia, 2022)Border cells are a specialized cell type surrounding the root apical meristematic region of many plant species, with the exception of the Brassicaceae family that possess characteristically different border-like cells. ...