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dc.contributor.advisorAtasoy, Ulus X.eng
dc.contributor.authorDahm, Garrett M.eng
dc.contributor.authorGubin, Matthew M.eng
dc.contributor.authorStellato, Christianaeng
dc.contributor.authorMagee, Joseph D.eng
dc.contributor.authorFang, Xieng
dc.contributor.authorFan, Jinshuieng
dc.contributor.authorCasolaro, Vincenzoeng
dc.contributor.authorTartar, Danielle, 1981-eng
dc.contributor.authorChen, Jing, 1962-eng
dc.contributor.authorJackson, Glenn A.eng
dc.contributor.authorFranklin, Craig L.eng
dc.contributor.corporatenameUniversity of Missouri--Columbia. School of Medicineeng
dc.date.issued2010eng
dc.description.abstractAsthma and other allergic inflammation diseases are major contributors to hospitalizations and deaths worldwide. These diseases are the result of over reactive immune responses initiating pro inflammatory mediators. These CD4+ T helper type 2 (Th2) mediated diseases are driven by the transcription factor GATA3 as well as the cytokines IL-4 and IL-13. HuR, an RNA binding protein (RBP), has been shown to posttranscriptionally regulate many early response genes, including these critical allergy mediators.eng
dc.identifier.urihttp://hdl.handle.net/10355/9196
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Day.eng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectrespiratory diseaseseng
dc.subjectgenetic factorseng
dc.subject.FASTGene expressioneng
dc.subject.FASTCytokineseng
dc.subject.FASTImmune responseeng
dc.titleCoordinate regulation of GATA3 and CD4+ T-helper 2 (TH2) cytokine gene expression by the RNA-binding protein HuR [abstract]eng
dc.typeOthereng


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