Development of high throughput tissue analysis laboratory [abstract]
Metadata[+] Show full item record
Boron neutron capture therapy (BNCT) is a promising binary radiation therapy for the treatment of cancer and other diseases. In order for this therapy to succeed, non-toxic compounds carrying boron-10 must be successfully transported into tumor cells. In a second step, the tumor is irradiated with low-energy neutrons, which are captured by boron-10 and result in a nuclear fission reaction. The products of this reaction, an alpha particle and lithium nuclei, travel a distance of less than 10 micrometers in tissue. In principle this therapy is highly targeted and specific, whereby the high-LET radiation created by the boron-neutron capture reaction is contained within the volume of a single cell.