Development of high throughput tissue analysis laboratory [abstract]

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Development of high throughput tissue analysis laboratory [abstract]

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Title: Development of high throughput tissue analysis laboratory [abstract]
Author: Eidson, Christine; Higdon, Sarah; Woody, James
Keywords: cancer treatment
biodistribution
Date: 2010-11-11
Abstract: Boron neutron capture therapy (BNCT) is a promising binary radiation therapy for the treatment of cancer and other diseases. In order for this therapy to succeed, non-toxic compounds carrying boron-10 must be successfully transported into tumor cells. In a second step, the tumor is irradiated with low-energy neutrons, which are captured by boron-10 and result in a nuclear fission reaction. The products of this reaction, an alpha particle and lithium nuclei, travel a distance of less than 10 micrometers in tissue. In principle this therapy is highly targeted and specific, whereby the high-LET radiation created by the boron-neutron capture reaction is contained within the volume of a single cell.
URI: http://hdl.handle.net/10355/9202

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