Biomedical Sciences Presentations (UMKC)
Items in this collection are the scholarly output of the Department of Biomedical Sciences faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format.
Items in MOspace are protected by copyright, with all rights reserved, unless otherwise indicated.
Recent Submissions
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Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by delta-tocotrienol and quercetin.
(2011-12-20)Abstract Background Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that ... -
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)Abstract Background Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ... -
Regulation of Phosphorylation of Dopamine D3 Receptors in Mouse Striatal Neurons in vivo
(2010-03)Introduction: Dopamine D3 receptors (D3Rs) are G-protein-coupled receptors. These D3Rs inhibit adenylyl cyclase and the downstream formation of cAMP. Due to their preferential expression in the mesolimbic areas, especially ... -
Amphetamine Alters Group I mGluR Expression in the Rat Striatum and Medial Prefrontal Cortex
(2010-03)Introduction: Group I metabotropic glutamate receptors (mGluR1/mGluR5 subtypes) and their key scaffolding protein Homer1b/c are densely expressed in the striatum. These receptors are believed to play important roles in ... -
Amphetamine Alters Acid-Sensing Ion Channel Expression in the Rat Striatum
(2010-03)Introduction: The acid-sensing ion channel (ASIC) is specifically activated by a drop in the extracellular pH level. These channels are widely expressed in mammalian brains and actively modulate synaptic transmission and ... -
Chronic Fibrotic Changes in Experimental Pulmonary Embolization in the Rat Model
(2010-03)Introduction: Fat embolism, a subclinical event, occurs in many clinical settings, such as long bones fractures, liposuction and during cardiopulmonary bypass. Some cases, especially with trauma, result in fat embolism ... -
Clearing the hurdles for nanotechnology: In vivo inhalation effects
(2010-03)INTRODUCTION: Nanoparticles of many types have been created for industrial and medical applications. Among these nanoparticles, single-walled carbon nanotubes (SWCNT) are of high interest for their physicochemical properties ... -
Acid-sensing ion channels as a novel target for drug addiction [abstract]
(2010-03)Improving the treatment and prevention of drug addiction is an important goal for modern medicine. Ion channels have recently become very attractive targets in the search of new pharmacotherapies. Extracellular proton ... -
Skeletal Muscle - Bone Crosstalk Regulating Osteocyte Function [abstract]
(2010-03)Osteocytes are thought to be the primary cell in bone that responds to mechanical loading and the traditional view is that skeletal muscle's role relative to bone is in the application of those loads. We have hypothesized ...