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dc.contributor.advisorMohan, Rajiv R.eng
dc.contributor.authorKillion, Elizabeth A.eng
dc.contributor.authorSharma, Ajayeng
dc.contributor.authorTovey, Jonathaneng
dc.contributor.authorTandon, Ashisheng
dc.contributor.authorGupta, Rangan, 1978-eng
dc.contributor.corporatenameUniversity of Missouri--Columbia. School of Medicineeng
dc.contributor.meetingnameHealth Sciences Research Day (2010 : University of Missouri)eng
dc.date.issued2010eng
dc.description.abstractTransforming growth factor β (TGFb) is associated with many corneal pathologies, diseases and dystrophies. The function of TGFb in adult corneas cannot be studied using conventional transgenic approach because TGFb1 and TGFb2 deficient transgenic animals suffer multiple inflammatory diseases, severe developmental defects, and death by 3-4 weeks of age. This study tested the hypothesis that selective tissue-targeted gene transfer approaches will permit examination of TGFb gene function in the adult cornea without altering TGFb expression in vital organs.eng
dc.format.extent1 pageeng
dc.identifier.urihttp://hdl.handle.net/10355/9243
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Dayeng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectcorneal abnormalitieseng
dc.subjecttherapeutic targetseng
dc.subject.FASTGenetic transformationeng
dc.subject.FASTCornea -- Diseaseseng
dc.titleGene transfer technology : a tool for studying gene function and role in corneal pathogenesis [abstract]eng
dc.typeAbstracteng


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