Getting over a hangover: how do wake promoting neurons in the basal forebrain affect ethanol induced sleep? [abstract]

Abstract

Hangover is a common clinical manifestation of heavy alcohol use. Sleepiness/drowsiness is a common symptom of hangover; however its neuroanatomical substrate is unknown. The basal forebrain (BF) cholinergic neurons play a central role in promoting wakefulness and are associated with sleep promoting effects of ethanol. Are the BF cholinergic neurons important for emerging from alcohol induced hangover/sleep?