dc.contributor.advisor | Thyfault, John P. | eng |
dc.contributor.author | Morris, E. Matthew | eng |
dc.contributor.author | Uptergrove, Grace M.E. | eng |
dc.contributor.author | Koch, Lauren | eng |
dc.contributor.author | Britton, Steve L. | eng |
dc.contributor.author | Ibdah, Jamal A. | eng |
dc.contributor.corporatename | University of Missouri--Columbia. School of Medicine | eng |
dc.contributor.meetingname | Health Sciences Research Day (2010 : University of Missouri) | eng |
dc.date.issued | 2010 | eng |
dc.description.abstract | Hepatic steatosis is commonly linked to hepatic insulin resistance. However, recent studies have found that increased hepatic triacylglycerol (TAG) accumulation is not always associated with impaired hepatic insulin signaling, leading to a hypothesis that partitioning of lipids into TAG in the liver matched with high rates of fatty acid oxidation (FAO) under high lipid exposure conditions may protect against hepatic insulin resistance. We examined this hypothesis in the livers of high and low capacity running (HCR/LCR) rats which were created by artificial selection based on differences in intrinsic aerobic capacity. | eng |
dc.format.extent | 1 page | eng |
dc.identifier.uri | http://hdl.handle.net/10355/9337 | |
dc.language | English | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. Health Sciences Research Day | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | hepatocytes | eng |
dc.subject | fatty liver | eng |
dc.subject.FAST | Fatty liver | eng |
dc.subject.FAST | Liver -- Diseases | eng |
dc.subject.FAST | Maximal oxygen uptake | eng |
dc.subject.FAST | Insulin resistance | eng |
dc.title | Intrinsic high aerobic capacity protects against lipid induced hepatic insulin resistance [abstract] | eng |
dc.type | Abstract | eng |