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dc.contributor.advisorThakkar, Mahesheng
dc.contributor.authorSharma, Rishieng
dc.contributor.authorMichael, Amandaeng
dc.contributor.authordeRoode, Davideng
dc.contributor.authorLodhi, Shafieng
dc.contributor.corporatenameUniversity of Missouri--Columbia. School of Medicineeng
dc.date.issued2010eng
dc.description.abstractNicotine (tobacco) addiction is a serious health issue and a leading cause of death. However, the mechanism of nicotine addiction is not fully understood. Previous reports suggest that nicotine induced activation of orexin neurons in the lateral hypothalamus (LH) region of the brain may play an important role in nicotine addiction. Adenosine is implicated to inhibit orexin neurons. Does nicotine reduce adenosine release in the LH and thereby causing disinhibition/ activation of orexin neurons?eng
dc.identifier.urihttp://hdl.handle.net/10355/9372
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Day.eng
dc.subjectchemical addictioneng
dc.subjecttobacco useeng
dc.subject.FASTNicotine addictioneng
dc.subject.FASTAdenosineeng
dc.subject.FASTHypothalamuseng
dc.titleNicotine reduces adenosine release in the lateral hypothalamus: a possible mechanism of its addiction [abstract]eng
dc.typeOthereng


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