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dc.contributor.advisorThakkar, Mahesheng
dc.contributor.authorMichael, Amandaeng
dc.contributor.authorSharma, Rishieng
dc.contributor.corporatenameUniversity of Missouri--Columbia. School of Medicineeng
dc.contributor.meetingnameHealth Sciences Research Day (2010 : University of Missouri)eng
dc.date.issued2010eng
dc.description.abstractInsomnia during alcohol withdrawal is a hallmark of alcohol dependency and a major cause of relapse in recovering alcoholics. The mechanism of insomnia in this patient population is poorly understood. Cholinergic neurons in the basal forebrain (BF) play an important role in promoting wakefulness. Recently, we have shown that acute ethanol/alcohol exposure inhibits these cholinergic neurons to promote sleep. Does chronic ethanol exposure lead to the persistent activation of the BF cholinergic neurons which may lead to insomnia?eng
dc.format.extent1 pageeng
dc.identifier.urihttp://hdl.handle.net/10355/9394
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Dayeng
dc.rightsOpenAccess.eng
dc.rights.licenseThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.eng
dc.subjectbinge drinkingeng
dc.subjectsleep/wake cycleeng
dc.subject.FASTAlcoholismeng
dc.subject.FASTCodependencyeng
dc.subject.FASTInsomniaeng
dc.subject.FASTProsencephaloneng
dc.titleProtracted activation of the basal forebrain cholinergic neurons after binge ethanol exposure [abstract]eng
dc.typeAbstracteng


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