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dc.contributor.advisorZaghouani, Habibeng
dc.contributor.authorCascio, Jasoneng
dc.contributor.authorHaymaker, Cara Lena, 1982-eng
dc.date.issued2010eng
dc.description.abstractThe phenomenon of oral tolerance is important for inducing non-reactivity to food borne antigens and commensal organisms by the immune system. In this study we have devised a method to induce tolerance to an auto-antigen, myelin oligodendrocyte glycoprotein (MOG), by oral administration of a chimeric immunoglobulin, Ig-MOG. Oral treatments with Ig-MOG ameliorated experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis (MS).eng
dc.identifier.urihttp://hdl.handle.net/10355/9402
dc.languageEnglisheng
dc.relation.ispartofcommunityUniversity of Missouri--Columbia. Health Sciences Research Day.eng
dc.subjectautoimmune disordereng
dc.subjectT cellseng
dc.titleReversal of CNS autoimmunity by induction of oral tolerance to brain antigens mediated by antigen presenting cells of the lamina propria [abstract]eng
dc.typeOthereng


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