dc.contributor.advisor | Zaghouani, Habib | eng |
dc.contributor.author | Cascio, Jason | eng |
dc.contributor.author | Haymaker, Cara Lena, 1982- | eng |
dc.contributor.meetingname | Health Sciences Research Day (2010 : University of Missouri) | eng |
dc.date.issued | 2010 | eng |
dc.description.abstract | The phenomenon of oral tolerance is important for inducing non-reactivity to food borne antigens and commensal organisms by the immune system. In this study we have devised a method to induce tolerance to an auto-antigen, myelin oligodendrocyte glycoprotein (MOG), by oral administration of a chimeric immunoglobulin, Ig-MOG. Oral treatments with Ig-MOG ameliorated experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis (MS). | eng |
dc.format.extent | 1 page | eng |
dc.identifier.uri | http://hdl.handle.net/10355/9402 | |
dc.language | English | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. Health Sciences Research Day | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | autoimmune disorder | eng |
dc.subject | T cells | eng |
dc.title | Reversal of CNS autoimmunity by induction of oral tolerance to brain antigens mediated by antigen presenting cells of the lamina propria [abstract] | eng |
dc.type | Abstract | eng |