The therapeutic role of resveratrol in allergic lung inflammation [abstract]
Metadata[+] Show full item record
Abstract CD4+ T helper type 2 (Th2) cells are crucial for mediating allergic inflammatory lung disease such as asthma, by producing key cytokines including interleukin (IL)-4, IL-5 and IL-13. The phytoalexin, resveratrol, which is rich in grapes and red wine, can increase lifespan and has been suggested as a potential reagent to treat aging-related diseases. Herein we report that resveratrol prevents mice from developing experimental asthma induced by ovalbumin sensitization and rechallenge.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.