Tissue-selective controlled decorin gene delivery in the rabbit cornea significantly retards corneal angiogenesis in vivo [abstract]
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TissueSelectiveControlledDecorin.pdf (223.7Kb)Abstract
Recent studies have shown that decorin gene therapy inhibits neovascularization in many non-ocular tissues. We tested the efficacy of decorin gene delivery into stroma with AAV5 to impede vascular endothelial growth factor (VEGF)-induced angiogenesis in rabbit cornea in vivo.
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