Long-acting β-agonists and inhaled corticosteroids for persistent asthma
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For adults with persistent asthma who remain symptomatic while using an inhaled corticosteroid (ICS), the addition of a long-acting β-agonist (LABA) reduces the rate of exacerbations, improves lung function and symptoms, and modestly decreases rescue use of short-acting β2-agonists. However, risk of death and intubation is slightly increased when LABAs are used with ICSs, compared with inhaled steroids alone.
Evidence Based Practice 13(10): 01-02.