Are diuretics safe and effective for lymphedema?
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Diuretics are not recommended for the treatment of lymphedema uncomplicated by other morbidities. Chronic diuretic use can cause electrolyte abnormalities and an overall worsening of the condition. (SOR: C, based on consensus guidelines.) Chlorothiazide is the only diuretic that has been studied.
Evidence-based practice 13, no. 11 (2010): 10-11