Are alpha-blockers effective for preventing recurrent acute urinary retention in adult men?
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Alfuzosin is not effective for the primary prevention of acute urinary retention (AUR) associated with benign prostatic hyperplasia (BPH) in adult men. (SOR: B, based on an RCT.) However, it is effective for secondary prevention for up to 3 months after an initial episode of AUR. (SOR: B, based on an RCT.) Doxazosin does not appear to be effective for preventing AUR. (SOR: C, extrapolated from a single RCT with both primary and secondary prevention as outcomes.)
Evidence Based Practice 13(12): 14.