How safe and effective are meningococcal vaccines?
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The meningococcal conjugate vaccines are safe (SOR: A,based on systematic review and multiple RCTs) and immunogenic. The conjugate vaccines provide a superior immune response--particularly in younger populations--compared with the older polysaccharide vaccines. Efficacy data are lacking because the disease is rare.
Evidence-based practice 13, no. 12 (2010): 10