• Genetic and microbiota-mediated phenotype variability in the min mouse model of human colorectal cancer 

  Moskowitz, Jacob E. (University of Missouri--Columbia, 2019)

  Complex diseases develop as a result of genetic predisposition and environmental factors that determine individual risk. Environmental factors such as geographical location, diet, and lifestyle choices shape the gut ...

• Defining recurrent laryngeal nerve injury in a mouse model for regenerative therapeutic investigations 

  Haney, Megan M. (University of Missouri--Columbia, 2019)

  Injury of the recurrent laryngeal nerve (RLN), a branch of the vagus nerve, results in ipsilateral vocal fold (VF) paralysis that contributes to dysphagia, dysphonia, and dyspnea (i.e., swallow, vocal, and respiratory ...

• Reflux, aspiration and respiratory disease in dogs : clinical consideration and advances in aerodigestive diagnostics 

  Grobman, Megan Elizabeth (University of Missouri--Columbia, 2019)

  The aspiration of gastric contents into the respiratory tract has been associated with the development and progression of multiple respiratory diseases in humans. In veterinary medicine the term “aspiration” is considered ...

• Morphological and biomechanical predictions of cranial kinesis in reptile evolution 

  Cost, Ian N. (University of Missouri--Columbia, 2019)

  Feeding is a complex behavior that all tetrapods engage in on a regular basis to procure energy and survive. The reptilian feeding apparatus includes many types of feeding behaviors including multiple methods of engaging ...

• Impacts of artificial light and melatonin signaling pathways on behavior and skeletal physiology in mice 

  Peacock, Sarah J. (University of Missouri--Columbia, 2019)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The natural cycles of light and darkness are a major feature of the environment for most species; thus, circadian physiology is rooted in the expectation ...

• Rat modeling of ovarian tissue cryopreservation and auto-grafting 

  Lehmidi, Tareq Mohamed Elhadi (University of Missouri--Columbia, 2019)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] New advancements in cancer treatment methods are increasing the survival rate of cancer patients. Unfortunately, these life-saving treatments, such ...

• Plastic and evolved morphological responses of the hind limb skeleton to mechanical loading in mice 

  Smolinsky, Amanda (University of Missouri--Columbia, 2018)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Skeletal morphology is determined by a combination of genetic background and phenotypic plasticity induced by mechanical loading. The changes in limb ...

• Epidemiology of non-aureus staphylococcal mastitis in dairy goats 

  Bernier Gosselin, Veronique (University of Missouri--Columbia, 2018)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The hypothesis of this work was that molecular-based speciation and strain-typing methods would help differentiate staphylococcal species with greater ...

• Ultrastructural damages in the brain induced by low-intensity primary blast wave : a transmission electron microscopy study on mild traumatic brain injury 

  Konan, Meleine Landry (University of Missouri--Columbia, 2018)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Explosive blast-induced mild traumatic brain injury (mTBI), a "signature wound" of recent military conflicts, commonly affects Service Members. While ...

• Avian [beta]-defensins as antimicrobial and immunomodulatory agents 

  Yang, Ming (University of Missouri--Columbia, 2018)

  The increasing prevalence of antibiotic-resistance and lack of effective antibiotics pose a serious threat to animal health and public health. Host antimicrobial peptides (AMPs) show broad-spectrum antimicrobial activity ...

• Mechanisms of Alphavirus Midgut dissemination in the Mosquito, Aedes aegypti 

  Kantor, Asher M. (University of Missouri--Columbia, 2018)

  The research work of this thesis has focused on the midgut escape barrier and the dissemination mechanism of alphaviruses in Ae. aegypti. Primarily, we identified and characterized Ae. aegypti MMPs that are seemingly ...

• Advancements in the understanding of staphylococcal mastitis through the use of molecular tools 

  Adkins, Pamela Rae Fry (University of Missouri--Columbia, 2017)

  The objectives of this work were: 1) to complete a whole genome sequence of a Staphylococcus chromogenes isolate that is known to persist in the mammary gland of a cow, 2) to define a genetic target that could easily and ...

• Bivalent peptide-based radioconjugates for prostate cancer imaging and potential therapy 

  Stott Reynolds, Tamila (University of Missouri--Columbia, 2017)

  [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Introduction: Despite decades of research, prostate cancer remains an important disease, with 1 out of 7 men diagnosed within his lifetime. In 2017, ...

• Dimorphism and integration in the pelves of anthropoid primates 

  Moffett, Elizabeth A. (University of Missouri--Columbia, 2016)

  The link between obstetric demand (natural selection for birth) and pelvic morphology in anthropoids has remained ambiguous for the past century. Though it is assumed that the dramatic sexual dimorphism seen in modern human ...

• RNA-sequencing analysis in B-cell acute lymphoblastic leukemia reveals aberrant gene expression and splicing alterations 

  Kholod, Olha (University of Missouri--Columbia, 2017)

  Background: B-cell acute lymphoblastic leukemia (B-ALL) is a neoplasm of immature lymphoid progenitors and is the leading cause of cancer-related death in children. The majority of B-ALL cases are characterized by recurring ...

• Computational modeling, ontogeny, and biomechanics of cranial forces in Alligator mississippiensis 

  Sellers, Kaleb Craig (University of Missouri--Columbia, 2015)

  3D computational modeling offers researchers tools to investigate forces in the skull during feeding and other behaviors. The American alligator and other crocodylians generate the highest bite forces among vertebrates, ...

• Archosaur hip joint anatomy and its significance in body size and locomotor evolution 

  Tsai, Henry P. (University of Missouri--Columbia, 2015)

  Archosaurs (crocodylians, birds and their extinct relatives) underwent numerous evolutionary transitions in limb morphology and body size, reflecting a diverse suite of postural and behavioral adaptations. Among archosaurs, ...

• Grasping pressures and phalangeal curvature in primates : an experimental in vivo approach 

  Congdon, Kimberly A. (University of Missouri--Columbia, 2015)

  Phalangeal curvature is often used to infer arboreal locomotion in fossil primate species. This is based off an hypothesis of plasticity linked to a loading model that suggests that, when flexed during grasping, a curved ...

• Global DNA methylation and gene expression analysis in pre-B cell acute lymphoblastic leukemia 

  Almamun, Md (University of Missouri--Columbia, 2015)

  Acute lymphoblastic leukemia (ALL) is a hematological cancer associated with precursor B-cells and is the most common cancer diagnosed in children under the age of 15. Our complete understanding of all mechanisms responsible ...

• Comprehensive profiling of micro RNA in human papillomavirus-associated squamous cell carcinoma of the head and neck 

  Miller, Daniel L. (University of Missouri--Columbia, 2014)

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