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Clinical translation of a novel cancer nanothereapeutic agent : bench to bedside from a small company perspective [abstract]
(2010-10)
Nanoparticles of gold are inherently multifunctional in their diagnostic and therapeutic capabilities. 198Au, provides a desirable beta energy emission and half-life for effective destruction of tumor cells/ tissue(?max = ...
AccrualMaster : software for planning and monitoring accrual rates in clinical trials [abstract]
(2010-10)
The most common reason why clinical trials fail is that they fall well below their goals for patient accrual. Researchers will frequently overpromise and underdeliver on the number of patients that they can recruit during ...
Construction and applications of engineered minichromosomes in plants
(2010-10)
The use of genetically modified crops is constantly finding new areas of application, including the production of compounds with therapeutic value. Current technology for producing transgenic crops relies on random ...
Soy based polyols [abstract]
(2010-10)
Commercialization of Natural Oil Polyols, or NOPs, began in the late '90s to satisfy demand for sustainable products. One of the largest applications of NOPs is for urethane foams, where both Ford and General Motors are ...
Treatment of cardiovascular risk factors, nitric oxide synthesis, and c-reactive protein using a combination therapy of vitamins and flavanoids [abstract]
(2010-10)
Researchers at the University of Missouri Kansas City have studied the synergistic effects of a novel combination of vitamins and flavanoids on cardiovascular risk factors, C-reactive protein levels, and nitric oxide ...
Wound care [abstract]
(2010-10)
The invention can be used as a wound care material for treating both hard and soft tissues in mammals. Wounds such as diabetic ulcers or other open wounds can be covered with this bioactive and biodegradable material to ...
Thomsen-Friedenreich (TF) antigen in nipple aspirate fluid: biomarker for breast cancer detection
(2010-10)
Early detection and diagnosis are critical to successful treatment of breast cancer. Currently available breast cancer screening tools such as mammography and breast examination miss up to 40% of early breast cancers, are ...
Late osteoblast/early osteocyte-like cell line for visualizing collagen assembly in living cells [abstract]
(2010-10)
Immortal cell lines representing the late osteoblast/early osteocyte phenotype have been generated that stably express a collagen-GFP or collagen-mCherry fusion protein to fluorescently label type I collagen fibrils either ...
A nanotechnology-based electrochemical DNA sensing apparatus and method [abstract]
(2010-10)
DNA is a code that contains the building instructions for all organisms and is the ultimate identification card. For example, the DNA code of a particular bacterium can tell if that particular strain of the bacterium is ...
Multi-mode nanothermite thrusters with tunable impulse [abstract]
(2010-10)
Microthrusters have applications in projectile guidance systems, and micro-nano-satellite control. Thrusters are an integral part of a guidance system that includes orientation and trajectory sensors and target recognition ...
New inhibitor suppresses foot-and-mouth disease (FMD) [abstract]
(2010-10)
Foot-and-mouth Disease Virus (FMDV) is a positive stranded picornavirus that can infect cloven-hoofed animals, such as cattle, pigs and sheep, and lead to severe losses in livestock production. The delay in eradication or ...
Nanopore-facilitated single molecule detection of circulating microRNAs in cancer patients
(2010-10)
Developing new technologies for cancer screening and early diagnosis is a critical issue for saving cancer patients' lives. MicroRNAs (miRNAs) are a class of short (~18-24-nt) non-coding RNAs molecules that regulate gene ...
Neutron and gamma ray spectroscopic detection system
(2010-10)
The Domestic Nuclear Detection Office's mission is to improve the nation's ability to detect unauthorized nuclear importation, and the office was allocated $1.2 billion to accomplish its goal. The office has invested heavily ...
Correcting vision problems with a novel tunable lens [abstract]
(2010-10)
Correction of age-related optical changes in the eye, such as presbyopia, has been increasingly important. Researchers at the University of Missouri-St. Louis have conceived of a new and improved adaptive liquid crystal ...
Accurate and affordable allergen quantification for the seed biotech industry
(2010-10)
Plant seeds provide a significant portion of the protein present in the human diet, but are also the major contributors of allergenic proteins that cause a majority of the reported cases of food-induced anaphylaxis in the ...
An affordable automotive hybrid transmission
(2010-10)
It is estimated that there are more than 70 automobile models on the road today that use hybrid transmission technology for improving the efficiency of automobile transportation. Most of these transmissions are of the ...
MedSocket: a personalized medical meta-search engine for questions at the point of care
(2010-10)
In the U.S., healthcare is a $2.4 trillion industry, and health information technology costs exceed $65 billion per year. Healthcare expenditures are currently at 17% of the U.S. Gross Domestic Product and are expected to ...
A system of efficient, cost-effective, and customizable vaccines for use with multiple vaccine candidates
(2010-10)
Most vaccines created today are costly to produce. In addition, the creation of new vaccines to combat emerging diseases such as novel influenza strains such as H1N1 and SARS is slow and not able to meet the demand early ...
Adsorbed natural gas (ANG) technology
(2010-10)
This invention teaches a method of manufacturing carbon so that it adsorbs large amounts of gas at low pressures due to the high surface area and associated nanopores. For example, a full tank of this carbon can hold more ...
Aluminim nitride vacuum ultraviolet photodiode [abstract]
(2010-10)
This invention teaches a method of creating a novel photodiode that will enable a significant improvement in data storage capacity over the Blu-Ray technology. More than 4x the amount of data could be held on a VUV storage ...