Effects of antisense-induced downregulation of circadian gene period1 in the basolateral amygdala on spontaneous sleep-wakefulness and consolidation of traumatic memory

Abstract

"The basolateral amygdala (BLA) significantly influences both the sleep-wake cycle and various memory functions, highlighting its intricate role in governing sleep regulation. The basolateral amygdala plays a crucial role in regulating the timing and coordination of the sleep-wake cycle through its involvement in circadian processes. Although many studies have not distinguished functional roles of the BLA, this study suggests that modulating the expression of the Period1(Per1) gene in the BLA has a role in regulation of the sleep-wake cycle."--Introduction.