How often do you need to change a PICC line?
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There is no need to routinely change a peripherally inserted central catheter (PICC) line to prevent infections. As long as the PICC line is functioning and there is no evidence of line-associated local or systemic infection, the PICC line can remain in place until it is no longer needed. (SOR: B, based on a single RCT and an evidence-based guideline with moderate level of evidence.)
Evidence Based Practice 14(1): 08-09.