What is the minimum number of days that antibiotics should be given to a patient hospitalized with uncomplicated pneumonia?
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Patients hospitalized with community-acquired pneumonia (CAP) should be treated for a minimum of 5 days. (SOR: A, based on meta-analysis of RCTs and an evidence-based guideline.) Clinically, it is important to realize that short-course protocols (especially with levofloxacin) often use higher daily doses than standard protocols. Patients should be afebrile for 48 to 72 hours and have symptom improvement before discontinuing treatment. (SOR: B, based on an evidence-based guideline with a moderate level of evidence.)
Evidence Based Practice 14(1): 12.