What is the role of montelukast in chronic idiopathic urticaria?
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Montelukast, a leukotriene receptor antagonist, provides mild relief but is less effective than antihistamines for treating patients with chronic idiopathic urticaria. (SOR: A, based on consistent RCTs.) Montelukast may provide additional symptom relief as add-on therapy with an antihistamine. (SOR: B, based on conflicting RCTs.)
Evidence Based Practice 14(1): 14.