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Recent Submissions

  • What should you tell pregnant women about exposure to parvovirus? 

    Snyder, Matthew; Wallace, Rick (Family Physicians Inquiries Network, 2011-12)
    Tell patients that parvovirus infections before 20 weeks' gestation confer a risk of fetal morbidity and mortality as high as 16%, but don't significantly increase long-term developmental sequelae (strength of recommendation ...
  • Ferning in amniotic fluid: Is it a useful indicator of ruptured membranes? 

    Gaddey, Heidi; Bailey, Justin; Smith, Rita (Family Physicians Inquiries Network, 2011-12)
    The presence of arborized crystals (ferning) in amniotic fluid is both sensitive (74%-100%) and specific (77%-100%) for diagnosing rupture of membranes in laboring women who report loss of fluid (strength of recommendation ...
  • Treatment of Nongenital Warts 

    Feigenbaum, Alyson L.; Ainsworth, Carla; St. Anna, Leilani (Family Physicians Inquiries Network, 2011-12)
    Topical salicylic acid, cryotherapy, and topical fluorouracil are effective for treating nongenital warts. (Strength of Recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs].) ...
  • What treatment is best for hypertrophic scars and keloids? 

    Williams, Carol C.; de Groote, Sandy (Family Physicians Inquiries Network, 2011-12)
    No one treatment is best (strength of recommendation [SOR]: C, meta-analysis of heterogenous studies); no good evidence exists comparing treatments with each other. Triamcinolone injections, triamcinolone injections ...
  • Should you test for H pylori in patients with nonulcer dyspepsia? 

    Lanier, J. Brian; Wilder, Laura (Family Physicians Inquiries Network, 2011-12)
    Helicobacter pylori in creases the risk of developing peptic ulcer disease (strength of recommendation [SOR]: B, cohort study), but there is no evidence that treating H pylori reduces that risk. Treating H pylori in patients ...
  • How can we minimize recurrent ankle sprains? 

    Hemphill, Brandon; Whitworth, James D.; Smith, Rita (Family Physicians Inquiries Network, 2011-12)
    Using external ankle supports during physical activity significantly reduces the likelihood of primary and secondary sprains (strength of recommendation [SOR]: A, systematic review). Proprioception rehabilitation ...
  • Antibody Testing for Systemic Lupus Erythematosus 

    Gibson, Kacey; Goodemote, Patricia; Johnson, Stephen (Family Physicians Inquiries Network, 2011-12)
    Antibody testing plays an important role when assessing patients, but should not be used alone to diagnose SLE. (Strength of Recommendation: C, based on expert opinion.) The antinuclear antibody (ANA) test is the most ...
  • Which regimen treats vitamin D deficiency most effectively? 

    Osborn, Justin; Germann, Antonio; St. Anna, Leilani (Family Physicians Inquiries Network, 2011-11)
    Several vitamin D replacement regimens are effective. Cumulative dosing may be more important than frequency of dosing (strength of recommendation [SOR]: C, inconsistent results from randomized controlled trials [RCTs] ...
  • Which combination drug therapies are most effective for hypertension? 

    Crawford, Paul; Dy, David; Carney, Misty (Family Physicians Inquiries Network, 2011-11)
    Insufficient evidence exists to determine which specific combinations most effectively decrease cardiovascular morbidity and mortality, although combinations of hypertension medications at lower doses generally reduce ...
  • What's best for croup? 

    Pitluk, Jessica Danielle; Uman, Howard; Safranek, Sarah (Family Physicians Inquiries Network, 2011-11)
    A single dose of corticosteroids is the first-line treatment for croup, resulting in fewer return visits and hospital admissions, shorter lengths of stay in the emergency department (ED) or hospital, and less need for ...
  • Ginger for the Treatment of Nausea and Vomiting in Pregnancy 

    Maitre, Sarah; Neher, Jon O.; Safranek, Sarah (Family Physicians Inquiries Network, 2011-11)
    Ginger can be safely used to reduce nausea and vomiting in pregnancy. (Strength of Recommendation [SOR]: B, based on small, heterogeneous trials comparing ginger with placebo and unproven comparators). Ginger's effectiveness ...
  • Antidepressants for the Treatment of Insomnia in Patients with Depression 

    Clark, Molly S.; Smith, Patrick O.; Jamieson, Barbara (Family Physicians Inquiries Network, 2011-11)
    There is no single antidepressant or class of antidepressants that is most effective for the treatment of insomnia in patients with depression. The use of antidepressant medications can have a positive impact on sleep ...
  • Treatment of Recurrent Vulvovaginal Candidiasis 

    Davis, J. Delrene; Harper, Amy (Family Physicians Inquiries Network, 2011-06)
    A six-month treatment regimen with an antifungal agent decreases the recurrence of vulvovaginal candidiasis. (Strength of Recommendation [SOR]: A, based on good-quality randomized controlled trials [RCTs].) For women in ...
  • Treatment of Hyperhidrosis 

    Saenz, John Woodrow; Jamieson, Barbara; Sams, Richard, II (Family Physicians Inquiries Network, 2011-02)
    OnabotulinumtoxinA injections (Botox; formerly botulinum toxin type A) are effective for the treatment of primary axillary and palmar hyperhidrosis. (Strength of Recommendation [SOR]: A, based on a systematic review of ...
  • Secondary Causes of Obesity 

    Allen, Ginger; Safranek, Sarah (Family Physicians Inquiries Network, 2011-04)
    Secondary causes of obesity can be detected by obtaining a patient history and performing a physical examination. Laboratory testing is recommended when additional findings are present, such as dysmorphic features, short ...
  • Reducing ACL Injuries in Female Athletes 

    Ringo, Shelley; Kelsberg, Gary; St. Anna, Leilani (Family Physicians Inquiries Network, 2011-01)
    Neuromuscular training programs that include plyometric and strengthening exercises significantly reduce noncontact ACL injuries in female soccer and handball players older than 14 years. (Strength of Recommendation: A, ...
  • Preventing Acute Mountain Sickness 

    Kitsteiner, John M.; Whitworth, James D.; Nashelsky, Joan (Family Physicians Inquiries Network, 2011-08)
    Gradual ascent is the most effective method for preventing acute mountain sickness. (Strength of Recommendation [SOR]: B, based on good-quality prospective and retrospective cohort studies.) Acetazolamide should be used ...
  • Hormone Therapy for Postmenopausal Women with Urinary Incontinence 

    Lee, Jay H.; Gomez, Suzanne; Jankowski, Terry Ann, 1951- (Family Physicians Inquiries Network, 2011-07)
    Postmenopausal women should not receive oral hormone therapy for treatment of urinary incontinence. Hormone therapy is associated with worsening urinary incontinence in postmenopausal women who are incontinent at baseline ...
  • Effective Therapies for Intermittent Claudication 

    Rudisill, Heather M.; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2011-09)
    Supervised exercise programs are recommended to produce clinically significant improvements in walking distance in patients with stable intermittent claudication. (Strength of Recommendation [SOR]: A, based on systematic ...
  • Clinical Indicators of Obstructive Sleep Apnea 

    Ghuman, Mandeep; Ludwig, Mary Jo; St. Anna, Leilani (Family Physicians Inquiries Network, 2011-05)
    Clinical indicators (e.g., sex, snoring severity, history of apnea, age, menopausal status, waist-to-hip ratio, body habitus) can predict OSA as diagnosed using overnight polysomnography or sleep study. (Strength of ...

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