Childhood alopecia areata: What treatment works best?

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Childhood alopecia areata: What treatment works best?

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/9951

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Title: Childhood alopecia areata: What treatment works best?
Author: Haynes, James W.; Persons, Robert K.; Jamieson, Barbara
Keywords: hair loss
hair regrowth
Date: 2011-01
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 60(1) 2011: 45+.
Series/Report no.: Clinical Inquiries;vol. 60, no. 2, 2010
Abstract: There are no validated effective treatments for alopecia areata (AA). Topical immunotherapy (squaric acid dibutylester [SADBE] and diphenylcyclopropenone [DPCP]) induces the most significant short-term hair regrowth in children with severe AA (strength of recommendation [SOR]: C, 4 small individual cohort studies and 1 moderately sized retrospective case review). Intralesional steroids can induce hair regrowth greater than 50% in children with limited AA (SOR: C, 1 retrospective cohort study). Other commonly used treatments—topical and oral corticosteroids, topical cyclosporine, photodynamic therapy, and topical minoxidil—have no benefit over placebo (SOR: A, 14 randomized controlled trials [RCTs] and 3 within-patient studies).
URI: http://hdl.handle.net/10355/9951

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