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    Childhood alopecia areata: What treatment works best?

    Haynes, James W.
    Persons, Robert K.
    Jamieson, Barbara
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    [PDF] ChildhoodAlopeciaAreata.pdf (115.1Kb)
    Date
    2011-01
    Metadata
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    Abstract
    There are no validated effective treatments for alopecia areata (AA). Topical immunotherapy (squaric acid dibutylester [SADBE] and diphenylcyclopropenone [DPCP]) induces the most significant short-term hair regrowth in children with severe AA (strength of recommendation [SOR]: C, 4 small individual cohort studies and 1 moderately sized retrospective case review). Intralesional steroids can induce hair regrowth greater than 50% in children with limited AA (SOR: C, 1 retrospective cohort study). Other commonly used treatments—topical and oral corticosteroids, topical cyclosporine, photodynamic therapy, and topical minoxidil—have no benefit over placebo (SOR: A, 14 randomized controlled trials [RCTs] and 3 within-patient studies).
    URI
    http://hdl.handle.net/10355/9951
    Part of
    Clinical Inquiries;vol. 60, no. 2, 2010
    Part of
    Clinical Inquiries, 2011 (MU)
    Citation
    Journal of Family Practice, 60(1) 2011: 45+.
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    • Clinical Inquiries, 2011

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